Technical Report: Medicine Selection and Use Technical Brief

South Africa remains at the center of the worldwide AIDS epidemic, with an estimated 5.6 million people living with the disease. In addition, the country has the third-highest burden of tuberculosis (TB) internationally. 1 South Africa’s unique disease burden shapes the country’s national health priorities, health system design, and health funding structures. The limited funds for medicines and medicine-related health technologies available under the National Health Insurance (NHI) fund must be allocated according to an evidence-based approach in order to provide the best quality of healthcare to all South Africans.